India’s new 3-dose Covid vaccine for 12-plus: What you should know | India News

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NEW DELHI: India is all set to roll out the world’s first DNA-based Covid vaccine which will be administered to children above 12 years of age as well as adults.
Zydus Cadila’s India-developed jab ZyCoV-D got regulatory approval on Friday for emergency use and the company is planning a commercial rollout around mid-September. This will effectively be the fourth Covid vaccine available for mass use in India after Covishield, Covaxin and Sputnik V. Overall, six vaccines have been approved for use in India.
Here are key things to know about India’s new anti-Covid shot …
* Unlike every other vaccine in use, ZyCoV-D will have a 3-dose regimen with a time interval of 28 days between each shot. All other anti-Covid shots in India are two-dose vaccines.
* The Zydus shot will be given using a needle-free applicator as opposed to a syringe. This is being done to help reduce the side-effects.
* The phase 3 interim results have showed that ZyCoV-D has primary efficacy of 66.6%. The company separately said that the vaccine is 66% effective against the delta variant, with higher antibody levels in the age group of 12 years and 18 years.
* Cadila is expected to supply around 5 crore doses by December this year. The company said it is planning to increase the production of the vaccine by up to 1 crore doses per month starting October this year with the help of a new production plant.
* The vaccine can be stored at 25 degrees celsius for 3 months.
* The price of the vaccine is not known yet and is expected to be finalised by next week.
* DNA & RNA-based vaccines. What are they? Vaccine uses a section of genetic material from virus that gives instructions as either DNA or RNA to make the specific protein that the immune system recognises and responds to.
“Plug-and-play” tech on which plasmic DNA platform is based can be easily adapted to deal with mutations.
Both US-based Moderna and Pfizer are mRNA vaccines. Covishield is a viral vector shot which uses modified, harmless virus to deliver instructions to the immune system while Covaxin uses an inactivated strain of the actual virus.
(With inputs from agencies)

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